Prof Dr. Stefan J Schaller

Forschung

Link zu Researchgate

Forschungsinteressen
Forschung Intensivmedizin
  • Frührehabilitation/mobilisation
  • Langzeitoutcome von Intensivpatienten
  • Ernährung des Intensivpatienten

Forschung Notfallmedizin
  • Schmerztherapie
  • Beatmung

Forschung Anästhesie



Bibliography und Kollaborationen

2020:

  • Nydahl P, Spindelmann E, Hermes C, Kaltwasser A, Schaller SJ. German Network for Early Mobilization: Impact for participants. Heart Lung. 2020;49(3):301-3.
  • Greco M, Schaller SJ, Galarza L, Weiss B, ESICM NCot. New scoring criteria for ESICM NEXT fellowship evaluation: toward improved fairness. Intensive care medicine. 2020;46(5):1052-3.
  • Ibarz M, Boumendil A, Haas LEM, Irazabal M, Flaatten H, de Lange DW, Morandi A, Andersen FH, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjolner J, Jung C, Marsh B, Moreno R, Oeyen S, Ohman CA, Bollen Pinto B, Soliman IW, Szczeklik W, Valentin A, Watson X, Zaferidis T, Guidet B, Artigas A and VIP study group*. Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study. Ann Intensive Care. 2020;10(1):56. (Schaller SJ part of the study group)
  • Bruno RR, Wernly B, Beil M, Muessig JM, Rahmel T, Graf T, Meybohm P, Schaller SJ, Allgauer S et al. Therapy limitation in octogenarians in German intensive care units is associated with a longer length of stay and increased 30 days mortality: A prospective multicenter study. Journal of critical care. 2020;60:58-63.
  • Azoulay E, De Waele J, Ferrer R, Staudinger T, Borkowska M, Povoa P, Iliopoulou K, Artigas A, Schaller SJ, Shankar-Hari M, et al. International variation in the management of severe COVID-19 patients. Crit Care. 2020;24(1):486.
  • Azoulay E, De Waele J, Ferrer R, Staudinger T, Borkowska M, Povoa P, Iliopoulou K, Artigas A, Schaller SJ, Shankar-Hari M, et al. Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak. Ann Intensive Care. 2020;10(1):110.
  • Guidet B, de Lange DW, Boumendil A, Leaver S, Watson X, Boulanger C, Szczeklik W, Artigas A, Morandi A, Andersen F, Zafeiridis T, Jung C, Moreno R, Walther S, Oeyen S, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjolner J, Flaatten H and VIP2 group*. The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive care medicine. 2020;46(1):57-69. (Schaller SJ part of the study group)
  • Ibarz, M., A. Boumendil, L. E. M. Haas, M. Irazabal, H. Flaatten, D. W. de Lange, A. Morandi, F. H. Andersen, G. Bertolini, M. Cecconi, S. Christensen, L. Faraldi, J. Fjolner, C. Jung, B. Marsh, R. Moreno, S. Oeyen, C. A. Ohman, B. Bollen Pinto, I. W. Soliman, W. Szczeklik, A. Valentin, X. Watson, T. Zaferidis, B. Guidet, A. Artigas, and VIP study group*. Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study. Ann Intensive Care. 2020;10:56. (Schaller SJ part of the study group)
  • De Bus L, Depuydt P, Steen J, Dhaese S, De Smet K, Tabah A, Akova M, Cotta MO, De Pascale G, Dimopoulos G, Fujitani S, Garnacho-Montero J, Leone M, Lipman J, Ostermann M, Paiva JA, Schouten J, Sjovall F, Timsit JF, Roberts JA, Zahar JR, Zand F, Zirpe K, De Waele JJ and Diana study group*. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive care medicine. 2020;46(7):1404-17. (Schaller SJ part of the study group)
  • Santer, P., M. H. Anstey, M. D. Patrocinio, B. Wibrow, B. Teja, D. Shay, S. Shaefi, C. S. Parsons, T. T. Houle, M. Eikermann, and Midas Study Group*. Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS): an international randomised clinical trial. Intensive care medicine 2020;46:1884-93. (Schaller SJ part of the study group)
  • Kuhn KF, Schaller SJ. Comment on Early versus delayed mobilization for in-hospital mortality and health-related quality of life among critically ill patients: a systematic review and meta-analysis (Okada et al., Journal of Intensive Care 2019). Journal of intensive care. 2020;8:21.
  • Nydahl P, Hermes C, Spindelmann E, Kaltwasser A, Schaller SJ. [The Early Mobilization Network]. Med Klin Intensivmed Notfmed. 2020.
  • Hill A, Heyland DK, Elke G, Schaller SJ, Stocker R, Haberthur C, et al. Meeting nutritional targets of critically ill patients by combined enteral and parenteral nutrition: review and rationale for the EFFORTcombo trial. Nutr Res Rev. 2020:1-9.
  • Schaller SJ, Fuest K, Ulm B, Schmid S, Bubb C, von Eisenhart-Rothe R, et al. Substitution of perioperative albumin deficiency disorders (SuperAdd) in adults undergoing vascular, abdominal, trauma, or orthopedic surgery: protocol for a randomized controlled trial. Trials. 2020;21(1):726.
  • Edel A, Reinhart K, Schaller SJ. [Critical statement on selected recommendations of the new German S3 Sepsis Guideline]. Med Klin Intensivmed Notfmed 2020;115:505-7.
  

2019:

 

2018:

  • Kirmeier E, Abad Gurumeta A, Alfredo et al. and the Popular Contributors*. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study. The Lancet Respiratory Medicine. 2018; 7(2):129 - 140 (*Schaller SJ is part of the Popular Contributors)
  • Muessig JM, Nia AM, Masyuk M, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, et al.: Clinical Frailty Scale (CFS) reliably stratifies octogenarians in German ICUs: a multicentre prospective cohort study. DOI: 10.1186/s12877-018-0847-7 BMC Geriatrics 2018; 18(1)
  • Schaller SJ, Nagashima M, Schönfelder M, et al. GTS-21 attenuates loss of body mass, muscle mass, and function in rats having systemic inflammation with and without disuse atrophy. Pflügers Archiv - European Journal of Physiology 2018; pp. 1-11.
  • Fuest K, Schaller SJ. Recent evidence on early mobilization in critical-Ill patients. Current opinion in anaesthesiology 2018;31:144-50.
  • Guidet B, Flaatten H, et al for the group VIPs*: Withholding or withdrawing of life-sustaining therapy in older adults (>/= 80 years) admitted to the intensive care unit. Intensive Care Med 2018 (* Schaller SJ is part of the VIP study group)
  • Schaller SJ, Nydahl P, Blobner M, Latronico N, Hodgson C. What does the EPICC trial really tell us? e-letter BMJ 2018
  • Dorfhuber F, Schaller SJ. Möglicher Einfluss von mechanischen Thoraxkompressionssystemen und supraglottischen Atemwegshilfen auf das Outcome nach einem Kreislaufstillstand. Notfall + Rettungsmedizin. 2018;21(8):697-700.


2017

  • Eikermann M, Schaller SJ, Kasotakis G, Anstey M, Houle T. Early goal-directed mobilisation after surgery - Authors' reply. Lancet 2017;389:695-6.
  • Flaatten H, De Lange DW, Morandi A, et al for the VIP1 study group*. The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (>/= 80 years). Intensive care medicine 2017;43:1820-8. (* Schaller SJ is part of the VIP study group)
  • Schaller SJ, Alam SM, Mao J, Zhao Y, Blobner M, Greenblatt DJ, Martyn JA: Pharmacokinetics cannot explain the increased effective dose requirement for morphine and midazolam in rats during their extended administration alone or in combination. J Pharm Pharmacol 2017; 69: 82-88

2016

  • Schaller SJ, Anstey M, Blobner M, Edrich T, Grabitz SD, Gradwohl-Matis I, Heim M, Houle T, Kurth T, Latronico N, Lee J, Meyer MJ, Peponis T, Talmor D, Velmahos GC, Waak K, Walz JM, Zafonte R, Eikermann M: Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. Lancet 2016; 388: 1377-1388
  • Schaller SJ, Lewald H: Clinical pharmacology and efficacy of sugammadex in the reversal of neuromuscular blockade. Expert Opin Drug Metab Toxicol 2016; 12: 1097-108
  • Schaller SJ, Stauble CG, Suemasa M, Heim M, Duarte IM, Mensch O, Bogdanski R, Lewald H, Eikermann M, Blobner M: The German Validation Study of the Surgical Intensive Care Unit Optimal Mobility Score. J Crit Care 2016; 32: 201-6
  • Kaufhold N, Schaller SJ, Stauble CG, Baumuller E, Ulm K, Blobner M, Fink H: Sugammadex and neostigmine dose-finding study for reversal of residual neuromuscular block at a train-of-four ratio of 0.2 (SUNDRO20). Br J Anaesth 2016; 116: 233-40


2015

  • Stauble CG, Stauble RB, Schaller SJ, Unterbuchner C, Fink H, Blobner M: Effects of single-shot and steady-state propofol anaesthesia on rocuronium dose-response relationship: a randomised trial. Acta Anaesthesiol Scand 2015; 59: 902-11
  • Nagashima M, Sasakawa T, Schaller SJ, Martyn JA: Block of postjunctional muscle-type acetylcholine receptors in vivo causes train-of-four fade in mice. Br J Anaesth 2015; 115: 122-7
  • Baumuller E, Schaller SJ, Chiquito Lama Y, Frick CG, Bauhofer T, Eikermann M, Fink H, Blobner M: Postoperative impairment of motor function at train-of-four ratio >/=0.9 cannot be improved by sugammadex (1 mg kg-1). Br J Anaesth2015; 114: 785-93
  • Blobner M, Frick CG, Stauble RB, Feussner H, Schaller SJ, Unterbuchner C, Lingg C, Geisler M, Fink H: Neuromuscular blockade improves surgical conditions (NISCO). Surg Endosc 2015; 29: 627-36


2014
Kramer C, Jordan D, Kretschmer A, Lehmeyer V, Kellermann K, Schaller SJ, Blobner M, Kochs EF, Fink H: Electromyographic permutation entropy quantifies diaphragmatic denervation and reinnervation. PLoS One2014; 9: e115754


2013

Schaller SJ, Fink H: Sugammadex as a reversal agent for neuromuscular block: an evidence-based review. Core Evid2013; 8: 57-67


2010

Schaller SJ, Fink H, Ulm K, Blobner M: Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block. Anesthesiology2010; 113: 1054-60